Company : Advatec Co., Ltd. (Innovated by AVS Innovation Co., Ltd.)
Title : Waste Management to Valued Product of Waste Lime Peels as A Cell Synapse Enhancer (Flavanone Glycosides) for the Application in Neuroprotection and Memory Effect
Award : Bronze Prize, Seoul International Invention Fair 2019

We have discovered the novel method for the extraction of flavanone glycoside from wasted lime peels and prepared as microcapsules for enhancing the synaptogenic ability of cortical astrocytes mainly due to increased secretion of transforming growth factor beta-1 (TGF-β1) by these cells. The conversion of wasted lime peel turns waste to the valued product which provides a high impact in the nutraceutical industry as a neuroprotective agent. As microcapsules, the flavanone glycoside is protected from change from external factors such as light, temperature and pH, as well as improving the shelf life of the finished product and controlling the release of the encapsulated compound. Protecting the encapsulated compound, improving stability and increasing the shelf life of the finished product, preventing incompatibilities within the formula, controlling the release of the encapsulated compound.